Product Name

• Voltaren 100 mg Suppository

Scientific Name

• Diclofenac Sodium 100 MG SUPP

Category Of Voltaren 100 mg Suppository

• Analgesic, Antipyretic & Anti-inflammatory

Mechanism Of Action Of diclofenac

• Diclofenac which belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs) which works by

1. Inhibits cyclooxygenase (COX)-1 and COX-2, thereby inhibiting prostaglandin synthesis
2. May also inhibit neutrophil aggregation/activation, inhibit chemotaxis, decrease proinflammatory cytokine level, and alter lymphocyte activity

• Therapeutic Indications Of
• Voltaren 100 mg Suppository
• joint, muscle or tendon pain
• attacks of gout; a common form of inflammatory arthritis that is very painful. It usually affects one joint at a time (often the big toe joint).
• pain and swelling after surgery
• sprains, strains, dislocations and fractures and other injuries
• gynecology problems such as period pain.
• Inflammation of the bones and joints such as rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.
• Back pain.

Method Of Administration Of Voltaren 100 mg Suppository

• Suppositories are designed for insertion into the back passage (rectum). Never take them by mouth.
• How to use:

1. Lie on one side with your knees pulled up towards your chest.
2. Gently push the suppository pointed end first into your back passage (rectum) with your finger.
3. Push the suppository in as far as possible
4. Lower your legs and, if possible, stay still for a few minutes.
5. If you feel as if you need to push the suppository out, try to resist this by lying still with your buttocks pressed together.
6. It is important to keep the suppository in the rectum to allow it to melt and the medicine to be absorbed.
7. Pushing the suppository high into the rectum with your finger will help to reduce this feeling.
8. Wash your hands.

• Not to exceed 150 mg of Diclofenac per day
• Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Voltaren 100 mg Suppository

• Stomach pain, heartburn, nausea, vomiting, diarrhea, indigestion, wind, loss of appetite
• Headache, dizziness, vertigo
• Skin rash or spots
• Raised levels of liver enzymes in the blood
• Irritation where the suppository is inserted

Pregnancy & Breastfeeding Precautions While Taking Voltaren 100 mg Suppository

• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
• Not preferred especially during the first 3 months

Non-Pharmacological Treatments & Advice To Reduce Pain

• A lot of people find relief from gentle massage, and some hospice agencies have volunteers who are trained in massage therapy.
• Relaxation techniques.
• Physical therapy
• Gel packs.

Warnings & Special Precautions while Taking Voltaren 100 mg Suppository

• Suppositories may also occasionally cause itching or burning in your back passage.
• Stop taking the medication and tell your doctor straight away if you notice:

1. Sudden and crushing chest pain (signs of myocardial infarction or heart attack)
2. Breathlessness, difficulty breathing when lying down, swelling of the feet or legs (signs of heart failure)
3. Sudden weakness or numbness in the face, arm or leg especially on one side of the body.
4. sudden loss or disturbance of vision; sudden difficulty in speaking or ability to understand speech; sudden migraine-like headaches which happen for the first time, with or without disturbed vision. These symptoms can be an early sign of a stroke.
5. Stomach pain, indigestion, heartburn, wind, nausea (feeling sick) or vomiting (being sick)
6. Any sign of bleeding in the stomach or intestine, for example, when emptying your bowels,
7. blood in vomit or black, tarry feces
8. Allergic reactions can include skin rash, itching, bruising, painful red areas, peeling or blistering

• Tell your doctor or pharmacist if you are taking any of the following:

1. Medicines to treat diabetes
2. Anticoagulants (blood-thinning tablets like warfarin)
3. Diuretics (water tablets)
4. Lithium (used to treat some mental problems)
5. Methotrexate (for some inflammatory diseases and some cancers)
6. Ciclosporin and tacrolimus (used to treat some inflammatory diseases and after transplants)
7. Trimethoprim (a medicine used to prevent or treat urinary tract infections)
8. Quinolone antibiotics (for infections)
9. Any other NSAID or COX-2 (cyclo-oxygenase-2) inhibitor, for example, aspirin or ibuprofen
10. Cardiac glycosides (for example digoxin), used to treat heart problems
11. Medicines known as SSRIs used to treat depression
12. Oral steroids (an anti-inflammatory drug)
13. Medicines used to treat heart conditions or high blood pressure, for example, beta blockers or ACE inhibitors
14. Voriconazole (a medicine used to treat fungal infections)
15. Phenytoin (a medicine used to treat seizures)
16. Colestipol/cholestyramine (used to lower cholesterol)

Storage Conditions Of Voltaren 100 mg Suppository

• store below 25°c
• Keep this medicine out of the sight and reach of children.
• Store in the original package to protect from moisture.
• Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

For More Information About diclofenac

• Ask your physician or pharmacist
• Visit Medscape at Information About Diclofenac
• Visit Drugbank at Information About Diclofenac
• Visit Drugs.com at Information About Diclofenac
• SFDA website