Product Name

• Teveten Plus, Reduce Blood Pressure, Prevent Hypertension Complication - 28 Tablets

Scientific Name

• Eprosartan 600 Mg + Hydrochlorothiazide 12.5 Mg Tablets

Category Of Teveten Plus Tablets

• Anti-Hypertensive Drugs

Mechanism Of Action Of Eprosartan & Hydrochlorothiazide

• Eprosartan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to constrict.
• As a result, Eprosartan relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart.
• Hydrochlorothiazide inhibits sodium chloride transport in the distal convoluted tubule. More sodium is then excreted in the kidney with accompanying fluid.
• Thus it increases urine excretion, which by turn decreases blood volume and finally blood pressure.
• On long-term usage, thiazide diuretic (TZD)-mediated chronic reduction of arterial pressure is thought to occur through decreased total peripheral vascular resistance.

Therapeutic Indications Of Teveten Plus Tablets

• Treating high blood pressure (hypertension) in adult patients when monotherapy with eprosartan or hydrochlorothiazide is not sufficient.
• High blood pressure is a common condition in which the long-term force of the blood against your artery walls is high enough that it may eventually cause health problems, such as heart disease.
• Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.

Method Of Administration Of Teveten Plus Tablets

• Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
• The tablets should be swallowed whole with a glass of water.
• You should try to take your daily dose at about the same time each day.
• You must continue to take the drug until your doctor tells you otherwise.
• Do not break the tablet in half
• You can take the tablet with or without food.
• The recommended dose is once daily but your doctor may increase the dose to reaches the targeted blood pressure
• Children and adolescents under 18 years should not take Eprosartan plus Hydrochlorothiazide.
• Do not take Eprosartan plus Hydrochlorothiazide if you have severe liver problems
• Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Teveten Plus Tablets

• Common side effects:

1. Feeling light-headed, dizzy, or faint
2. Headache
3. Tiredness, fatigue, or weakness
4. Trouble sleeping
5. Diarrhea, feeling sick (nausea), or vomiting
6. Stomach pain or discomfort
7. Joint pain
8. Urinary tract infection
9. Cough

• Uncommon side effects:

1. Muscle aches and pains
2. Signs of frequent or worrying infections such as fever, severe chills, sore throat, or mouth ulcers
3. Yellowing of the skin and eyes also called jaundice
4. Numbness or tingling in the hands or feet
5. Skin rash, itchiness

Pregnancy & Breastfeeding Precautions While Taking Teveten Plus Tablets

• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Non-Pharmacological Treatments & Advice To Reduce Blood Pressure

• To measure blood pressure correctly:

1. Don’t eat or drink anything 30 minutes before you take your blood pressure.
2. Empty your bladder before your reading.
3. Sit in a comfortable chair with your back supported for at least 5 minutes before your reading.
4. Put both feet flat on the ground and keep your legs uncrossed.
5. Rest your arm with the cuff on a table at chest height.
6. Make sure the blood pressure cuff is snug but not too tight. The cuff should be against your bare skin, not over clothing.
7. Do not talk while your blood pressure is being measured.

• You will also find the following Non-Pharmacological treatments effective in blood pressure reduction:

1. Lose extra pounds and watch your waistline
2. Exercise regularly
3. Eat a healthy diet
4. Reduce sodium in your diet
5. Quit smoking
6. Reduce caffeine
7. Reduce your stress
8. Monitor your blood pressure at home using for example Beurer, Blood Pressure Monitor or Omron Blood Pressure Measuring Device
9. See your doctor regularly

Warnings & Special Precautions while Taking Teveten Plus Tablets

• Stop using the product and seek immediate medical attention if you developed: Swelling of the face, lips, tongue, or throat which may cause difficulty in breathing or swallowing
• You should let your doctor know:

1. If you think that you are (or might become) pregnant. Eprosartan plus Hydrochlorothiazide is not recommended in early pregnancy
2. And must not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if used at that stage
3. If you are dehydrated or have low salt levels (because you are on a low salt diet, are taking water tablets or you suffered from diarrhea or vomiting). These conditions should be corrected before you start taking Eprosartan plus Hydrochlorothiazide
4. If you know you have raised potassium levels in your blood
5. If you suffer from heart disease e.g. Heart valve disease, an enlarged heart, or weakness of the heart muscle (heart failure)
6. If you have severe kidney problems, have had a kidney transplant, or need dialysis
7. If you have a narrowing or a blockage of the blood vessels leading to your kidney(s)
8. If you have any other liver problems
9. If you have gout
10. If you have a condition affecting your adrenal gland (hyperaldosteronism)
11. If you are of Afro-Caribbean origin, as Eprosartan plus Hydrochlorothiazide may be less effective in lowering blood pressure
12. If you are taking any medicines used to treat high blood pressure

• Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. This includes medicines obtained without a prescription, or the following:

1. Other high blood pressure medicines, especially ACE inhibitors, medicines that contain aliskiren, or diuretics (water or (fluid tablets)
2. Medicines affecting potassium levels
3. Non-steroidal anti-inflammatory drugs (NSAIDs), medicines used to relieve pain, swelling, and other symptoms of inflammation
4. Diabetes medication
5. Heart medication
6. Gout medication
7. Muscle relaxants
8. Medications used to treat psychiatric conditions, and epilepsy.
9. Parkinson's medication
10. Laxatives, corticosteroids, and adrenocorticotropic hormone (ACTH)
11. Cancer medication
12. Calcium and vitamin D supplement

Storage Conditions Of Teveten Plus Tablets

• Store below 25°c
• Don’t refrigerate
• Keep this medicine out of the sight and reach of children.
• Store in the original package to protect from moisture.
• Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

Normal Ranges

• Normal: Blood pressure numbers of less than 120/80 mm Hg
• Elevated: is when readings consistently range from 120-129 systolic and less than 80 mm Hg diastolic.
• Hypertension Stage 1: is when blood pressure consistently ranges from 130-139 systolic or 80-89 mm Hg diastolic.
• Hypertension Stage 2: is when blood pressure consistently ranges at 140/90 mm Hg or higher.
• Hypertensive crisis: This stage of high blood pressure requires medical attention. If your blood pressure readings suddenly exceed 180/120 mm Hg, wait five minutes and then test your blood pressure again. If your readings are still unusually high, contact your doctor immediately. You could be experiencing a hypertensive crisis.

For More Information About Eprosartan & Hydrochlorothiazide

• Ask your physician or pharmacist
• Visit SFDA website
• Visit Medscape at Information About Eprosartan & Hydrochlorothiazide
• Visit Drugs.com at Information About Eprosartan & Hydrochlorothiazide