Metabolic and Cellular Engineering ‎(‎MCE‎)‎ is more than an exciting scientific enterprise‎.‎ It has become the cornerstone for coping with the challenges ahead of mankind‎.‎ Continuous developments‎,‎ new concepts‎,‎ and technological innovations will enable us to deal with emerging challenges‎,‎ and solve problems once thought impossible ten years ago‎.‎ Challenges in MCE are broad‎- from unraveling fundamental aspects of cellular function to meeting unsatiated energy and food demands that are rising in parallel with population growth‎.‎In charting the progress of MCE during the last decade‎,‎ we could not help but feel in awe of the enormous strides of progress made from the nascent Metabolic Engineering to the Systems Bioengineering of today‎.‎ The burgeoning availability of genomic sequences from diverse species has been spectacular‎.‎ It has become the engine that drives the genetic means for the modification of existing organisms and the generation of synthetic‎,‎ man‎-made ones‎.‎ From the initial attempts at purposeful genetic modification of a cell for the production of valuable compounds‎,‎ we have now moved on to changing microbes genetically or metabolically‎.‎The arsenal of experimental and theoretical tools available for Metabolic and Cellular Engineering has expanded enormously‎,‎ driven by the re‎-emergence of Physiology as Systems Biology‎.‎ The revival of the concept of networks fueled by new developments has become central to Systems Biology‎.‎ Networks represent an integrative vision of how processes of disparate nature relate to each other‎,‎ and as such is becoming a key analytical and conceptual tool for MCE‎.‎ This book reflects and addresses all these ongoing changes while providing the essential conceptual and analytical tools needed to understand and work in the MCE research field‎.‎

• Author‎:‎ S‎.‎ Cortassa‎,‎ M‎.‎ A‎.‎ Aon‎,‎ A‎.‎ A‎.‎ Iglesias ‎,‎ J‎.‎ C‎.‎ Aon
• Publisher‎:‎ World Scientific Publishing
• ISBN‎:‎ 9789814365727