Product Name

• Lorvast 10 Mg, Reduce Blood Cholesterol Level & Prevent Hyperlipidemia Complications - 30 Tablets

Scientific Name

• Atorvastatin 10 Mg Tablets

Category Of Lorvast 10 Mg Tablets

• Anti-Hypercholesterolemia Drugs

Mechanism Of Action Of Atorvastatin

• Atorvastatin is a cholesterol-lowering medication that belongs to the statin class of drugs. Statins lower cholesterol levels in the blood by blocking 3-hydroxy-3-methylglutaryl coenzyme A(HMG-CoA) reductase, an enzyme that's needed for the liver to produce cholesterol.
• Decreased hepatic cholesterol concentrations stimulate the upregulation of hepatic low-density lipoprotein (LDL) receptors, which increases hepatic uptake of LDL & decreases LDL level in the blood.

Therapeutic Indications Of Lorvast 10 Mg Tablets

• It is used to lower lipids known as cholesterol and triglycerides in the blood when a low-fat diet and lifestyle changes on their own have failed.
• Cholesterol is a naturally occurring substance in the body necessary for normal growth. However, if there is too much cholesterol in your blood, it can build up on blood vessel walls, increasing the risk of blood clots and cardiovascular events. This is one of the most common causes of heart disease.
• If you are at an increased risk of heart disease, it can also be used to reduce such risk even if your cholesterol levels are normal.
• You should maintain a standard cholesterol-lowering diet during treatment.

Method Of Administration Of Lorvast 10 Mg Tablets

• The usual starting dose of Atorvastatin is 10 mg once a day in adults and children aged 10 years or older.
• This may be increased if necessary by your doctor until you are taking the amount you need
• Atorvastatin tablets should be swallowed whole with a drink of water, with or without food.
• Atorvastatin tablets can be taken at any time of day, but the most common instruction is to take your statin at night. This is because cholesterol production is thought to be highest at night
• Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Lorvast 10 Mg Tablets

1. Although the following side effects are not common in everyone, some patients may complain from:
2. Inflammation of the nasal passages, pain in the throat, nose bleed
3. Allergic reactions
4. Increases in blood sugar levels
5. Headache
6. Nausea, constipation, wind, indigestion, diarrhea
7. Joint pain, muscle pain, and back pain
8. Blood test results that show your liver function can become abnormal rash, skin rash and itching, hives, hair loss
9. Neck pain, muscle fatigue
10. Fatigue, feeling unwell, weakness, chest pain, swelling especially in the ankles (edema), raised temperature
11. Muscle weakness, tenderness, pain, rupture. Ron-Co Q10 Capsules may help to reduce muscle pain

Pregnancy & Breastfeeding Precautions While Taking Lorvast 10 Mg Tablets

• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
• Your doctor will discuss the possible risks and benefits of using this medicine during pregnancy and breast-feeding

Non-Pharmacological Treatments & Advice To Reduce Cholesterol Level In The Blood

• Reduce saturated fats. Saturated fats, found primarily in red meat and full-fat dairy products, raise your total cholesterol.
• Eliminate trans fats. Trans fats, sometimes listed on food labels as "partially hydrogenated vegetable oil," are often used in margarine and store-bought cookies, crackers, and cakes. Trans fats raise overall cholesterol levels.
• Eat foods rich in omega-3 fatty acids or use an omega-3 supplement like Omegat Omega 3 Capsules or Paradox Omega 3 Capsules
• Increase soluble fiber. Soluble fiber can reduce the absorption of cholesterol into your bloodstream. Soluble fiber is found in such foods as oatmeal, kidney beans, Brussels sprouts, apples, and pears.
• Exercise on most days of the week and increase your physical activity, work up to at least 30 minutes of exercise five times a week
• Quitting smoking improves your HDL cholesterol level.
• Losing weight will help you to reduce your triglyceride levels. A 5–10 percent weight loss can decrease triglyceride levels by 20 percent. Rondiet Capsules & Ronfit Capsules will help you to decrease your body weight
• Sometimes healthy lifestyle changes aren't enough to lower cholesterol levels. If your doctor recommends medication to help lower your cholesterol, take it as prescribed while continuing your lifestyle changes. Lifestyle changes can help you keep your medication dose low.

Warnings & Special Precautions while Taking Lorvast 10 Mg Tablets

• Do not take Atorvastatin:

1. If you are allergic to atorvastatin or any of the other ingredients of this medicine
2. If you have or have ever had a disease that affects the liver
3. If you have had any unexplained abnormal blood tests for liver function
4. If you are a woman able to have children and not using reliable contraception
5. If you are pregnant or trying to become pregnant
6. If you are breastfeeding
7. If you use the combination of glecaprevir/pibrentasvir in the treatment of hepatitis C
8. Talk to your doctor, pharmacist, or nurse before taking Atorvastatin:
9. If you have severe respiratory failure
10. If you are taking or have taken in the last 7 days a medicine called fusidic acid, (a medicine for bacterial infection) orally or by injection. The combination of fusidic acid and Atorvastatin can lead to serious muscle problems (rhabdomyolysis)
11. If you have had a previous stroke with bleeding into the brain, or have small pockets of fluid in the brain from previous strokes
12. If you have kidney problems
13. If you have an under-active thyroid gland (hypothyroidism)
14. If you have had repeated or unexplained muscle aches or pains
15. If you have a personal history or family history of muscle problems
16. If you have had previous muscular problems during treatment with other lipid-lowering medicines (e.g. Other ‘-statin’ or ‘-fibrate’ medicines)
17. If you have a history of liver disease
18. If you are older than 70 years

• Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription

Storage Conditions Of Lorvast 10 Mg Tablets

• Store below 25°c
• Don’t refrigerate
• Keep this medicine out of the sight and reach of children.
• Store in the original package to protect from moisture.
• Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

Normal Ranges

• According to MedlinePlus
• Anyone age 19 or younger:

1. Total Cholesterol: Less than 170 mg/dL
2. Non-HDL: Less than 120 mg/dL
3. LDL: Less than 100 mg/dL
4. HDL: More than 45 mg/dL

• Men age 20 or older:

1. Total Cholesterol: 125 to 200 mg/dL
2. Non-HDL: Less than 130 mg/dL
3. LDL: Less than 100 mg/dL
4. HDL: 40 mg/dL or higher

• Women age 20 or older:

1. Total Cholesterol: 125 to 200 mg/dL
2. Non-HDL: Less than 130 mg/dL
3. LDL: Less than 100 mg/dL
4. HDL: 50 mg/dL or higher

• The exact values may be changed based on the used guideline

For More Information About Atorvastatin

• Ask your physician or pharmacist
• Visit SFDA website
• Visit Medscape at Information About Atorvastatin
• Visit Drugs.com at Information About Atorvastatin
• Visit Drugbank.com at Information About Atorvastatin