Product Name

• Glyxambi, Empagliflozin/Linagliptin, Tablet, 10/5 Mg - 30 Tablets

Scientific Name

• Empagliflozin 10 Mg + Linagliptin 5 Mg Tablets

Category Of Glyxambi 10/5 Tablets

• Oral Anti-Diabetic Drugs

Mechanism Of Action Of Empagliflozin

• Empagliflozin works by inhibiting the sodium-glucose co-transporter-2 (SGLT-2) found in the proximal tubules in the kidneys. Through SGLT2 inhibition, empagliflozin reduces renal reabsorption of glucose and increases urinary excretion of glucose.

Therapeutic Indications Of Glyxambi 10/5 Tablets

• Empagliflozin is used to treat type 2 diabetes in adult patients (aged 18 years and older) that cannot be controlled by diet and exercise alone.
• Empagliflozin can be used without other medicines in patients who cannot take metformin (another diabetes medicine).
• Empagliflozin can also be used with other medicines for the treatment of diabetes. These may be medicines taken by mouth or given by injection such as insulin.
• It is important that you continue with your diet and exercise plan as told by your doctor, pharmacist or nurse

Method Of Administration Of Glyxambi 10/5 Tablets

• Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure
• Do not change your dose unless your doctor has told you to. Swallow the tablet whole with water
• You can take the tablet with or without food
• You can take the tablet at any time of the day. However, try to take it at the same time each day. This will help you to remember to take it.
• Appropriate diet and exercise help your body use its blood sugar better. It is important to stay on the diet and exercise program recommended by your doctor while taking Empagliflozin
• Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Glyxambi 10/5 Tablets

• Although the following side effects are not common in everyone, some patients may complain from:

1. Low blood sugar (hypoglycaemia)
2. Urinary tract infection
3. Genital yeast infection (thrush)
4. Polyuria
5. Itching
6. Rash or red skin
7. Thirst
8. Blood tests may show an increase in blood fat (cholesterol) levels in your blood

Pregnancy & Breastfeeding Precautions While Taking Glyxambi 10/5 Tablets

• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
• Your doctor will discuss the possible risks and benefits of using this medicine during pregnancy and breast-feeding

Non-Pharmacological Treatments & Advice For Diabetic Patients

• All carbohydrates affect blood glucose levels so it’s important to know which foods contain carbohydrates. Choose the healthier foods that contain carbs and be aware of your portion sizes.
• Eat less salt. Eating lots of salt can increase your risk of high blood pressure, which in turn increases the risk of heart diseases and stroke. And when you have diabetes, you’re already more at risk of all of these conditions.
• Eat more fruit and vegetables. This can help you get the vitamins, minerals, and fiber your body needs every day to help keep you healthy.
• You can always try low or zero-calorie sweeteners (also known as artificial sweeteners) to help you cut down sugar for example Steviana Sweetener or Tropicana Slim Sweetener
• Don’t forget to keep moving. Being more physically active goes hand in hand with eating healthier.
• Remember to measure your blood glucose level continuously by using home monitor like Accu-Check, Instant, Blood Glucose Monitor
• Thiozac Capsules & Neurobion Tablets will help you to reduce neuropathy induced by diabetes
• If you experience symptoms of hypoglycemia such as weakness, dizziness, increased sweating, fast heart beating, vision disorders or difficulty in concentration, it usually helps to eat or drink something containing sugar.

Warnings & Special Precautions while Taking Glyxambi 10/5 Tablets

• Talk to your doctor, pharmacist or nurse before taking this medicine, and during treatment:

1. If you have “type 1 diabetes”.
2. If you experience rapid weight loss, feeling sick or being sick
3. If you have serious kidney or liver problems
4. If you might be at risk of dehydration (severe diarrhea for example)
5. If you are 85 years old or older
6. If you have a serious infection of the kidney or the urinary tract with fever.

• Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medications including over-the-counter non-prescription medicines, prescription medicines, herbal supplements, vitamins, and supplements.

Storage Conditions Of Glyxambi 10/5 Tablets

• Store below 25°c
• Don’t refrigerate
• Keep this medicine out of the sight and reach of children.
• Store in the original package to protect from moisture.
• Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

Normal Ranges

• Random blood sugar test: A blood sample will be taken at a random time. Regardless of when you last ate, a blood sugar level of 200 milligrams per deciliter (mg/dL) or higher suggests diabetes. A blood sugar level less than 140 mg/dL is normal. A reading between 140 and 199 mg/dL indicates prediabetes
• Fasting blood sugar test. A blood sample will be taken after an overnight fast. A fasting blood sugar level less than 100 mg/dl is normal. A fasting blood sugar level from 100 to 125 mg/dL is considered prediabetes. If it's 126 mg/dL or higher on two separate tests, you may have diabetes.
• Oral glucose tolerance test: For this test, you fast overnight, and the fasting blood sugar level is measured. Then you drink a sugary liquid, and blood sugar levels are tested periodically for the next two hours.

For More Information About Empagliflozin

• Ask your physician or pharmacist
• Visit SFDA website
• Visit Medscape at Information About Empagliflozin
• Visit Drugs.com at Information About Empagliflozin
• Visit Drugbank.com at Information About Empagliflozin