Product Name

• Clexane 80 Mg, Anticoagulant, Reduce Risk Of Blood Clotting - 2 Syringes

Scientific Name

• Enoxaparin 80 Mg Injection

Category Of Clexane 80 Mg Syringe

• Anti-Coagulants Drugs

Mechanism Of Action Of Enoxaparin

• It binds to and potentiates antithrombin III, a serine protease inhibitor, to form a complex that irreversibly inactivates factor Xa.
• Enoxaparin has less activity against factor IIa (thrombin) compared to unfractionated heparin.

Therapeutic Indications Of Clexane 80 Mg Syringe

• Treat blood clots that are in your blood.
• Stop blood clots from forming in your blood in the following situations:
• Before and after an operation
• When you have an acute illness and face a period of limited mobility
• When you have unstable angina (a condition when not enough blood gets to your heart)
• After a heart attack
• Stop blood clots forming in the tubes of your dialysis machine (used for people with severe kidney problems).

Method Of Administration Of Clexane 80 Mg Syringe

• Your doctor or nurse will normally give you Enoxaparin. This is because it needs to be given as an injection.
• When you go home, you may need to continue to use Enoxaparin and give it yourself. Enoxaparin is usually given by injection underneath the skin (subcutaneous).
• Enoxaparin can be given by injection into your vein (intravenous) after certain types of heart attack or operation.
• Enoxaparin can be added to the tube leaving the body (arterial line) at the start of the dialysis session.
• Do not inject Enoxaparin into a muscle.
• Your doctor will decide how much Enoxaparin to give you. The amount will depend on the reason it is being used.
• Always take your medicine exactly as your doctor told you. If you are unsure about how to take your medicine, ask your doctor or pharmacist.
• Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Clexane 80 Mg Syringe

• Although the following side effects are not common in everyone, some patients may complain from:

1. You bruise more easily than usual. This could be because of a blood problem with low platelet counts.
2. Pink patches on your skin. These are more likely to appear in the area you have been injected with Enoxaparin.
3. Skin rash (hives, urticaria).
4. Itchy red skin.
5. Bruising or pain at the injection site.
6. Decreased red blood cell count.
7. High platelet counts in the blood.
8. Headache.

Pregnancy & Breastfeeding Precautions While Taking Clexane 80 Mg Syringe

• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
• Your doctor will discuss the possible risks and benefits of using this medicine during pregnancy and breast-feeding

Non-Pharmacological Treatments & Advice To Reduce Blood Clotting

• Wear loose-fitting clothes, socks, or stockings.
• Wear special stockings (called compression stockings) if your doctor prescribes them.
• Do exercises your doctor gives you.
• Change your position often, especially during a long trip.
• Do not stand or sit for more than 1 hour at a time.
• Take all medicines the doctor prescribes you.

Warnings & Special Precautions while Taking Clexane 80 Mg Syringe

• Talk to your doctor, pharmacist, or nurse before you take this medicine if you have any of The following:

1. you have ever had a reaction to heparin that caused a severe drop in the number of your platelets
2. you are going to receive spinal or epidural anesthesia or lumbar puncture
3. you have had a heart valve fitted
4. you have endocarditis (an infection of the inner lining of the heart)
5. you have a history of gastric ulcer
6. you have had a recent stroke
7. you have high blood pressure
8. you have diabetes or problems with blood vessels in the eye caused by diabetes (called diabetic retinopathy)
9. you have had an operation recently on your eyes or brain
10. you are elderly (over 65 years old) and especially if you are over 75 years old
11. you have kidney problems
12. you have liver problems
13. you are underweight or overweight
14. you have a high level of potassium in your blood (this may be checked with a blood test)
15. you are currently using medicines that affect bleeding

• Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medications including over-the-counter non-prescription medicines, prescription medicines, herbal supplements, vitamins, and supplements.

Storage Conditions Of Clexane 80 Mg Syringe

• Store below 25°c
• Don’t refrigerate
• Keep this medicine out of the sight and reach of children.
• Store in the original package to protect from moisture.
• Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

For More Information About Enoxaparin

• Ask your physician or pharmacist
• Visit https://www.sfda.gov.sa/en/drugs-list
• Visit Medscape at Information About Enoxaparin
• Visit Drugs.com at Information About Enoxaparin
• Visit Drugbank.com at Information About Enoxaparin