* Indications:  Intestinal amoebiasis.  Hepatic amoebiasis.  Urogenital trichomoniasis.  Giardiasis.* Contraindications:  Known hypersensitivity to imidazole derivatives.  Pregnancy and lactation.* Precautions:  – Avoiding administration in patients who had blood dyscrasias.  – Avoid alcohol consumption during treatment with secnidazole.* Dosage:  # Acute intestinal amoebiasis: 1-day treatment.  Adults: 2 gm (4 tablets) as a single dose.  Children: 30 mg/kg at a single dose.  # Chronic intestinal amoebiasis (cystic form): 3-day treatment.  – Adults: 2 gm (4 tablets) in a single daily dose for 3 days.  Children: 30 mg/kg in a single daily dose for 3 days.  # Hepatic amoebiasis: 5-day treatment.  – Adults: 1.5 gm (3 tablets) in a single daily dose for 5 days.  Children: 30 mg/kg in a single daily dose for 5 days.  # Urogenital trichomoniasis: 1-day treatment.  Adults: 2 gm (4 tablets) as a single dose.  Children: 30 mg/kg at a single dose.  NB: To take the tablets at the beginning of the meal.