This collection seeks to elucidate the practical methods necessary for successful adjuvant development‎,‎ with a particular focus on the synthesis‎,‎ formulation‎,‎ manufacturing‎,‎ and characterization aspects involved‎.‎ Beginning with an overview and a case study‎,‎ the book then delves into in silico design‎,‎ chemical synthesis‎,‎ biosynthesis‎,‎ and/or purification from natural raw materials of specific adjuvant molecules‎,‎ adjuvant formulation approaches‎,‎ the analytical characterization of adjuvant formulations and adjuvant‎-containing vaccines‎,‎ as well as the biological characterization of vaccine adjuvant activity‎,‎ including in vitro and in vivo approaches‎,‎ to measure innate and adaptive immune responses‎.‎ Written in the highly successful Methods in Molecular Biology format‎,‎ chapters include introductions to their respective topics‎,‎ lists of the necessary materials and reagents‎,‎ step‎-by‎-step‎,‎ readily reproducible laboratory protocols‎,‎ and tips on troubleshooting and avoiding known pitfalls‎.‎ Practical and authoritative‎,‎ Vaccine Adjuvants‎:‎ Methods and Protocols aims to facilitate vaccine adjuvant product development efforts‎,‎ making them more accessible‎,‎ manufacturable‎,‎ and better characterized‎.‎

• Author‎:‎ Christopher B‎.‎ Fox
• Publisher‎:‎ Springer
• ISBN‎:‎ 9781493964437