The volume aim to be a comprehensive overview of the drug and biologic development process that is often called ‎"‎the valley of death‎"‎ ‎(‎pre‎-IND through approval‎)‎ where high costs of studies and high rates of product failure are part of the drug development landscape‎.‎ Imaging tools can serve in this period by adding high value data‎,‎ the images and the kinetic information they can provide‎,‎ and cost‎-effective development alternative tools which potentially improve pivotal study designs‎.‎ Imaging may identify safety issues early such as unwanted organ or tissue distributions‎,‎ and then can serve advanced development with added certainty of a drug or biologic‎'‎s success to senior corporate management and investors‎.‎ There are numerous textbooks‎,‎ reference texts and treatises on medical imaging technologies‎,‎ teaching tools on medical cases and physics books on the science of detector and computer interface systems‎.‎ Rarely‎,‎ in each of these are examples of medical imaging protocols and animal models of disease i‎.‎e‎.‎ a text on methodology in drug development is currently unavailable‎.‎

• Author‎:‎ Brian R‎.‎ Moyer‎,‎ Narayan P‎.‎ S‎.‎ Cheruvu
• Publisher‎:‎ Springer
• ISBN‎:‎ 9781461482468