Efficient mobile systems that allow for vital sign monitoring and disease diagnosis at the point of care can help combat issues such as rising healthcare costs‎,‎ treatment delays in remote and resource‎-poor areas‎,‎ and the global shortage of skilled medical personnel‎.‎ Covering everything from sensors‎,‎ systems‎,‎ and software to integration‎,‎ usability‎,‎ and regulatory challenges‎,‎ mobile point‎-of‎-care monitors and diagnostic device design offers valuable insight into state‎-of‎-the‎-art technologies‎,‎ research‎,‎ and methods for designing personal diagnostic and ambulatory healthcare devices‎.‎ Presenting the combined expertise of contributors from various fields‎,‎ this multidisciplinary text‎:‎ * gives an overview of the latest mobile health and point‎-of‎-care technologies * discusses portable diagnostics devices and sensors‎,‎ including mobile‎-phone‎-based health systems * explores lab‎-on‎-chip systems as well as energy‎-efficient solutions for mobile point‎-of‎-care monitors * addresses computer vision and signal processing for real‎-time diagnostics * considers interface design for lay healthcare providers and home users mobile point‎-of‎-care monitors and diagnostic device design provides important background information about the design process of mobile health and point‎-of‎-care devices‎,‎ using practical examples to illustrate key aspects related to instrumentation‎,‎ information processing‎,‎ and implementation‎.‎