Perindopril belongs to Angiotensin-converting-enzyme inhibitors which are a class of medication used primarily for the treatment of high blood pressure and heart failure. They work by causing relaxation of blood vessels as well as a decrease in blood volume, which leads to lower blood pressure and decreased oxygen demand from the heart.
In addition, Perindopril blocks the conversion of angiotensin I to angiotensin II and prevents the degradation of vasodilator prostaglandins, thereby inhibiting systemic vasoconstriction, regulated by angiotensin II, and promoting systemic vasodilation.
Therapeutic Indications Of Coversyl 10 Mg Tablets
To treat hypertension (high blood pressure): high blood pressure is a common condition in which the long-term force of the blood against your artery walls is high enough that it may eventually cause health problems, such as heart disease.
To treat heart failure (which is a disorder that makes your heart muscle unable to pump blood properly)
To decrease the risk of cardiac events, like heart attack, in patients with stable coronary artery
Disease (a disorder where the blood supply to the heart is blocked or decreased) and in patients who have previously had a heart attack and/or an operation to enhance the blood supply to the heart by widening the blood vessels.
Method Of Administration Of Coversyl 10 Mg Tablets
Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
Swallow the tablet with a drink of water.
Take a tablet before food in the morning.
High blood pressure:
The recommended dose is 5 mg once daily. The dose can be increased to 10 mg once a day if needed after one month.
The maximum dose is 10 mg a day.
If you are 65 or older, the recommended initial dose is 2.5mg orally once daily. The dose may be increased to 5 mg once daily after a month and then to 10 mg once a day if needed.
The recommended dose is 2.5 mg orally once a day. The dose may be increased to 5mg once daily after 2 weeks.
The maximum recommended dose is 5 mg once daily.
Stable coronary artery disease:
The recommended initial dose is 5 mg once a day. The dose may be increased to 10 mg once daily after 2 weeks.
The maximum recommended dose is 10 mg once daily.
If you are 65 years of age or older, the recommended initial dose is 2.5 mg once daily. The dose may be increased to 5 mg once daily after a week and to 10 mg once a day after another week.
The use of this medicine is not recommended in children and adolescents.
Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
If you take more than you should, talk to a doctor or go to the hospital straight away.
If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
Do not take a double dose (two doses at the same time) to make up for the forgotten dose.
Undesirable Side Effects Of Coversyl 10 Mg Tablets
Allergic reaction (such as itching and skin rash).
Pregnancy & Breastfeeding Precautions While Taking Coversyl 10 Mg Tablets
If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Non-Pharmacological Treatments & Advice To Reduce Blood Pressure
To measure blood pressure correctly:
Don’t eat or drink anything 30 minutes before you take your blood pressure.
Empty your bladder before your reading.
Sit in a comfortable chair with your back supported for at least 5 minutes before your reading.
Put both feet flat on the ground and keep your legs uncrossed.
Rest your arm with the cuff on a table at chest height.
Make sure the blood pressure cuff is snug but not too tight. The cuff should be against your bare skin, not over clothing.
Do not talk while your blood pressure is being measured.
You will also find the following Non-Pharmacological treatments effective in blood pressure reduction:
Lose extra pounds and watch your waistline
Eat a healthy diet
Reduce sodium in your diet
Reduce your stress
Monitor your blood pressure at home using for example Beurer, Blood Pressure Monitor or Omron Blood Pressure Measuring Device
See your doctor regularly
Warnings & Special Precautions while Taking Coversyl 10 Mg Tablets
Stop the medication right away and talk to your doctor or pharmacist if you develop allergic reactions such as shortness of breath, skin rash, swelling of the face or neck, decreased blood pressure and dizziness.
Talk to your doctor if you have hypertrophic cardiomyopathy (heart muscle problem), aortic stenosis (main blood vessel that leads to the heart becomes narrowed) or renal artery stenosis (artery supplying blood to the kidney becomes narrow).
Talk to your doctor before starting this medicine if you have liver or kidney problems or if you are undergoing dialysis.
Talk to your doctor before starting this medicine if you have diabetes.
Talk to your doctor before starting this medicine if you have collagen vascular disease (disorder of the connective tissue) like scleroderma or systemic lupus erythematosus.
Talk to your doctor before starting this medicine if you are following a salt restricted diet or are using salt substitutes that have potassium.
Talk to your doctor before starting this medicine if you are to have LDL apheresis (cholesterol removal from your blood using a machine)
Talk to your doctor before starting this medicine if you are due to have a surgery and/or anesthesia.
Talk to your doctor before starting this medicine if you are going to undergo a desensitization therapy to decrease the effects of wasp stings or a bee allergy.
Talk to your doctor before starting this medicine if you are intolerant to some sugars.
Talk to your doctor before starting this medicine if you have recently suffered from vomiting, diarrhea or are dehydrated.
Talk to your doctor before starting this medicine if you are pregnant or plan on getting pregnant.
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medications including over the counter non-prescription medicines, prescription medicines, herbal supplements, vitamins and supplements.
Storage Conditions Of Coversyl 10 Mg Tablets
Store below 25°c
Keep this medicine out of the sight and reach of children.
Store in the original package to protect from moisture.
Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.
Normal: Blood pressure numbers of less than 120/80 mm Hg
Elevated: is when readings consistently range from 120-129 systolic and less than 80 mm Hg diastolic.
Hypertension Stage 1: is when blood pressure consistently ranges from 130-139 systolic or 80-89 mm Hg diastolic.
Hypertension Stage 2: is when blood pressure consistently ranges at 140/90 mm Hg or higher.
Hypertensive crisis: This stage of high blood pressure requires medical attention. If your blood pressure readings suddenly exceed 180/120 mm Hg, wait five minutes and then test your blood pressure again. If your readings are still unusually high, contact your doctor immediately. You could be experiencing a hypertensive crisis.