This manual walks students through the procedures for analysis in SPSS and provides exercises that go hand-in-hand with online data sets. The manual complements the textbook Understanding Political Science Statistics: Observations and Expectations in Political Analysis, by Peter Galderisi, making it easy to use alongside the book in a course or as a stand-alone guide to using SPSS. Galderisi demonstrates how to use both syntax and GUI driven formats and shows sample results of the analyses. Filled with annotated screenshots from SPSS version 22 (but compatible with all versions, including the student version), the students will be guided through standard processes replete with examples and exercises to ready them for future work in political science research. The diverse group of data sets provided include subsamples of both the 2008 and 2012 American National Election Studies, a Eurobarometer survey, single year and longitudinal congressional district files, the 2012 Comparative Congressional Election Study data set, and a comparative, crossnational country file. Versions with reduced case numbers and variables are also included that are compatible with the student version. This manual (and a parallel Stata manual) are available as stand-alone products or packaged with the textbook Understanding Political Science Statistics.