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ACTEMRA 200 MG / 10 ML 1 VIAL Details

  • The best price of ACTEMRA 200 MG / 10 ML 1 VIAL by Seif in Egypt is 3,639 EGP
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  • Similar products to ACTEMRA 200 MG / 10 ML 1 VIAL are sold at Seif with prices starting at 20.40 EGP
  • The first appearance of this product was on Nov 05, 2014
  • Amongst similar products of ACTEMRA 200 MG / 10 ML 1 VIAL the cheapest price is 20.40 EGP from Seif

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Seif's Description

** Actemra (Tocilizumab) 200 mg/10 ml (20 mg/ml) 1 vial of 10 ml of concentrate for solution for infusion.

** For i.v. use after dilution.

** 1 vial contains: 200 mg tocilizumab, polysorbate 80, sucrose, disodium phosphate dodecahydrate, sodium dihydrogen phosphate dehydrate and water for injections.

** Indications:

Rheumatoid arthritis; juvenile idiopathic arthritis; Castleman’s disease.

– Rheumatoid Arthritis (RA):

ACTEMRA® (tocilizumab) is indicated for the treatment of adult patients with moderately to severely active rheumatoid arthritis who have had an inadequate response to one or more Disease-Modifying Anti-Rheumatic Drugs (DMARDs).

– Polyarticular Juvenile Idiopathic Arthritis (PJIA):

ACTEMRA® (tocilizumab) is indicated for the treatment of active polyarticular juvenile idiopathic arthritis in patients 2 years of age and older.

– Systemic Juvenile Idiopathic Arthritis (SJIA):

ACTEMRA® (tocilizumab) is indicated for the treatment of active systemic juvenile idiopathic arthritis in patients 2 years of age and older.

** Pharmacotherapeutic group:

Immunosupressants, Interleukin inhibitors; ATC code: L04AC07.

** Mechanism of Action

Tocilizumab binds specifically to both soluble and membrane-bound IL-6 receptors (sIL-6R and mIL-6R), and has been shown to inhibit IL-6-mediated signaling through these receptors. IL-6 is a pleiotropic pro-inflammatory cytokine produced by a variety of cell types including T- and B-cells, lymphocytes, monocytes and fibroblasts. IL-6 has been shown to be involved in diverse physiological processes such as T-cell activation, induction of immunoglobulin secretion, initiation of hepatic acute phase protein synthesis, and stimulation of hematopoietic precursor cell proliferation and differentiation. IL-6 is also produced by synovial and endothelial cells leading to local production of IL-6 in joints affected by inflammatory processes such as rheumatoid arthritis.

** Medicine: keep out of reach of children.

** Dosage and administration: see package insert.

** Store between 2 – 8 degrees C, do not freeze. Keep the container in the outer carton in order to protect from light.

** Made for: F. Hoffmann-La Roche Ltd, Basel – Switzerland by: Chugai Pharma Manufacturing Co., Ltd., Utsunomiya-city – Japan استيراد : الشركة المصرية لتجارة الأدوية

ACTEMRA 200 MG / 10 ML 1 VIAL Price insights and history

  • The cheapest price of ACTEMRA 200 MG / 10 ML 1 VIAL in Egypt was 72.50 EGP from Seif within the past 76 months
  • The highest price of ACTEMRA 200 MG / 10 ML 1 VIAL in Egypt was 3,639 EGP from Seif within the past 76 months
  • The price difference between the cheapest and highest price of ACTEMRA 200 MG / 10 ML 1 VIAL in Egypt is 3,566.50 EGP from Seif within the past 76 months
  • The average price of ACTEMRA 200 MG / 10 ML 1 VIAL in Egypt is 1,855.75 EGP from Seif within the past 76 months

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