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CAIRO BOOKS's Description
Integrated Genomics: A Discovery-Based Laboratory Course introduces the
excitement of discovery to the basic molecular biology laboratory. Utilizing
up-to-date molecular biology protocols and a basic experimental design, this
text offers experience with three different model systems. Students will become
familiar with the simplicity and power of single-celled organisms, Escherichia
coli and Saccharomyces cerevisiae, as they search for genes that interact and
function within the nematode Caenorhabditis elegans .
Incorporated throughout the course are exercises designed to offer students
familiarity with the wealth of bioinformatics data that can be accessed on the
World Wide Web. Following completion of interaction studies within the yeast,
the course is designed to allow students to examine the functional consequences
of reducing a gene’s function within the multicellular worm that is both simple
and inexpensive to maintain within a laboratory. The inclusion of alternative
experiments allow for flexibility in determining the ending date or goal of the
laboratory, as well as working within the available budget and resources of
most any classroom environment.
Further striking features of this title are: An accompanying Web site
providing PowerPoint slides, plus links to the internet, and regular updates as
bioinformatics databases evolve and methods improve. www.wiley.com/go/caldwell
Inclusion of modern genomic/proteomic technologies such as the yeast two-hybrid
system and RNAi Detailed experimental protocols and easy access to
This discovery-based laboratory course provides excellent practical training
for those pursuing career paths in biomedicine, pharmacy, and biotechnology.