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CAIRO BOOKS's Description
Asymmetric synthesis has become a major aspect of modern organic chemistry.
The stereochemical properties of an organic compound are often essential to its
bioactivity, and the need for stereochemically pure pharmaceutical products is
a key example of the importance of stereochemical control in organic synthesis.
However, achieving high levels of stereoselectivity in the synthesis of complex
natural products represents a considerable intellectual and practical challenge
Written from a synthetic organic chemistry perspective, this text provides a
practical overview of the field, illustrating a wide range of transformations
that can be achieved. The book captures the latest advances in asymmetric
catalysis with emphasis placed on non-enzymatic methods.
Topics covered include: Reduction of alkenes, ketones and imines Nucleophilic
addition to carbonyl compounds Catalytic carbon-carbon bond forming reactions
Catalytic reactions involving metal carbenoids Conjugate addition reactions
Catalysis in Asymmetric Synthesis bridges the gap between undergraduate and
advanced level textbooks and provides a convenient point of entry to the
primary literature for the experienced synthetic organic chemist.