In Aliens‎:‎ Colonial Marines‎,‎ players are part of a United States Colonial Marine squad and must prepare to face an Aliens assault more intense and horrific than ever before‎.‎ Players must destroy the enemy with classic Aliens weaponry ranging from pulse rifles to flamethrowers as well as brand‎-new equipment‎.‎

Aliens‎:‎ Colonial Marines features a story driven single‎-player mode and a four player co‎-op mode allowing players to share the chilling experience with three friends‎.‎ In co‎-op mode‎,‎ each player assumes the persona of a United States Colonial Marine and have a distinct role to play in the completion of every mission‎.‎