* Epoetin 4000 I.U. Sedico 1 vial / 1 ml. Alpha Recombinant Human Erythropoietin. For S.C. or I.V. injection.* Composition:  Alpha Recombinant Human Erythropoietin 4000 I.U. + Albumin (human) 2.5 mg / vial.* Indications:  - Treatment of anemia of chronic renal failure patients. including patients on dialysis.  - Treatment of anemia in Zidovudine-treated HIV infected patients.  - Treatment of anemia in cancer patients on chemotherapy.  - Reduction of allogenic blood transfusion in surgery patients.* Contraindications:  - Uncontrolled hypertension.  - Known hypersensitivity to mammalian-cell derived products.  - Known hypersensitivity to human albumin.* Dosage:  # Chronic renal failure patients:  - Doses over the range of 50 to 100 units / kg 3 times weekly have been shown to be safe and effective.  - The dose should be reduced as the hematocrit approaches 36% or increases by more than 4 points in  any 2-weeks period.  - The dose must be individualized to maintain the hematocrit within the suggested target range.  # Zidovudine-treated HIV infected patients:  - The recommended starting dose is 100 units / kg as an I.V. or S.C. injection 3 times weekly and the dose  may be increased every 4-8 weeks by 50 to 100 units / kg 3 times weekly.  - If the hematocrit exceeds 40% the dose should be discontinued until the hematocrit drops to 36%.  # Cancer patients on chemotherapy:  - The recommended starting dose is 150 units / kg S.C. 3 times weekly.  - Dose adjustment: if the response is not satisfactory, the dose can be increased up to 300 units / kg 3 times weekly.  - If the hematocrit exceeds 40% the dose should be discontinued until the hematocrit drops to 36%.  # Surgery patients:  - The recommended dose is 300 units / kg / day S.C. for 10 days before surgery, on the day of surgery,  and for 4 days after surgery.* Keep at temp. from 2 to 8 oC. Avoid freezing and shaking.* Produced by: SEDICO Pharmaceutical Co. - Egypt.* Code: 6221042550016