Cancer is a very rare disease in children‎.‎ There have been impressive gains in survival in recent years‎,‎ and these have been achieved through the use of chemotherapy and national and international clinical trials‎.‎ The diagnosis of cancer in a child imposes considerable stress on the whole family‎.‎ In the immediate time after diagnosis‎,‎ parents must learn about the disease and its treatment‎,‎ explain what is happening to the child‎,‎ and make arrangements for the care of other children in the family‎.‎ For the child‎,‎ treatment is associated with many side effects depending on the specific drugs used‎.‎ In addition‎,‎ the child is prone to infection and therefore is likely to miss a lot of school and other activities‎.‎ For all these reasons‎,‎ physicians and families have become aware that cancer has huge implications for the quality of the child‎'‎s life‎.‎ This book is an attempt to describe how quality of life is affected at different stages of the disease process‎.‎ Comprehensive reviews are provided of the impact on the child‎'‎s physical activity‎,‎ social life‎,‎ and school and educational achievements‎.‎ Special consideration is given to children with leukemia ‎(‎one of the more common cancers‎)‎ and brain tumors‎.‎ Cancer does not just affect the child but every member of the family‎.‎ Consequently there is coverage of the effects on parents and also healthy brothers and sisters‎.‎ To the extent that improvements in survival have been achieved by national and international collaboration between clinicians‎,‎ it is concluded that efforts to improve the quality of these children‎'‎s lives is dependent on collaboration between clinicians‎,‎ nurses‎,‎ and behavioral scientists at national and international levels‎.‎ This book should provide an impetus for such collaboration‎.‎