A confident and attractive smile comes with bright white teeth and the health of your mouth. That's why new Colgate Total 12 Advanced Whitening toothpaste has a unique formula that not only helps remove stains for whiter teeth, but also keeps your whole mouth healthy by fighting bacteria on teeth, tongue, cheeks and gums for 12 hours. Experience the unique difference of a confident, bright and healthy smile with our best toothpaste for you. Directions for use: Brush thoroughly with a Colgate toothbrush, at least twice a day, or as directed by a dentist or physician. Children 6 years and under should have adult supervision and use only a pea sized amount to minimize swallowing.